Process HPLC Column, RP C4, 5um, 100A. 50mm ID x 100mm Length. Cogent Brand. 1 EA. Special Order Item.
Additional Information:
Cogent RP C4™ is a reversed-phase HPLC stationary phase designed for process-scale purification of hydrophobic and neutral compounds. Manufactured using a four-carbon butyl ligand bonded to ultra-high purity silica and fully double end capped, this stationary phase provides reproducible chromatographic performance and lower hydrophobic retention than C8 phases. The chemistry is particularly useful for process HPLC applications where high sample loading, efficient recovery, and robust performance are required.
68504-P50-100 is a process HPLC column packed with 5 µm RP C4™ particles featuring a 100 Å pore size in a 50 mm ID x 100 mm format. The large 50 mm internal diameter provides substantial loading capacity for production and process-scale purification, while the 100 mm length offers an excellent balance between throughput and chromatographic resolution. The 5 µm particles support high flow rates while maintaining acceptable operating pressures. Typical operating flow rates are approximately 80–150 mL/min depending on mobile phase composition, analyte characteristics, and system capabilities.
This column is particularly useful for process purification of hydrophobic and neutral compounds in pharmaceutical, chemical, and manufacturing environments. Compared to C8 and C18 phases, the C4 bonded phase provides lower retention, which can improve recovery and reduce cycle times. Due to its size and flow requirements, a specialized process HPLC system is required for operation.
Key Benefits
RP C4™ stationary phase
USP L26 equivalent chemistry
Butyl (C4) bonded phase
Fully double end capped
Ultra-high purity silica support
Less retention than C8 phases
High loading capacity
Supports high flow rates
5 µm particle size
Optimized for process HPLC
Typical Applications
Process HPLC
Process-scale purification
Small molecule purification
Pharmaceutical manufacturing
Chemical purification
Hydrophobic compound purification
Neutral compound purification
Fraction collection
Process development
Production-scale chromatography
Specifications
Product Type: Process HPLC Column
Stationary Phase: RP C4™
USP Classification: L26
Chromatography Mode: Reversed Phase
Bonded Phase: Butyl (C4)
Endcapping: Fully Double End Capped
Particle Size: 5 µm
Pore Size: 100 Å
Column Dimensions: 50 mm ID x 100 mm
Length: 100 mm
Typical Flow Rate: 80–150 mL/min
Brand: Cogent
Special Order Item Information
Important Notes
Designed for process-scale purification of hydrophobic and neutral compounds
Provides less retention than C8 stationary phases
High loading capacity for production-scale applications
The 50 mm ID format requires a specialized process HPLC system
Typical operating flow rates are approximately 80–150 mL/min
5 µm particles provide robust performance with manageable backpressure
Fully double end capped to minimize secondary interactions
The 100 mm length provides an effective balance of throughput and resolution
Excellent choice for process purification and manufacturing applications
This is a Special Order Item